• (+33) 169867131
  • neucrest@gmail.com

ABOUT US

The NEUcrest project is an Innovative Training Network coordinated by the Institut Curie, France and funded by the EU’s Horizon 2020 grant No. 860635.

Consortium Map
NEUcrest in numbers
  • Beneficiaries 11
  • Associated partners 9
  • Early Stage Researchers (Ph.D. students) 15
  • Overall budget € 4 156 404,84
  • Implementation period 1 Nov. 2019 – 31 Oct. 2023
NEUcrest research objectives
  • ► Identification of candidate genes and mutations from neurocristopathy patients
  • ► Develop a unified strategy to identify new genetic and environmental factors that contribute to neural crest related diseases
  • ► Set up a searchable database for neurocristopathies
  • ► Develop new drug targets for therapeutics

The neural crest (NC) lineage is a specialised multipotent embryonic tissue, which contributes notably to the development of the human peripheral and enteric nervous system, craniofacial structures, pigment cells, as well as many other tissues and organs. Neurocristopathies, diseases of NC-derived tissues are an acute societal problem.

The aim of the NEUcrest project is to train 15 creative and innovative PhD students within a novel, ambitious and interdisciplinary research program. This network is aimed at considering the overall genetic, molecular and epigenetic regulation of the NC tissue in human health.

The cumulative expertise of consortium members will provide an exceptional environment for PhD students, both for excellent research training and multiple transferable skills. This will allow the PhD students optimal career development and employability, through their acquired expertise in manipulating cells and embryos in various animal models, analyzing biological images and datasets, and modelling complex genetic interactions.

With an exceptionally rich training environment and regular network-wide events, our aim is to train 15 PhD students to be part of the next generation of leading European young scientists, highly proficient in the multidisciplinary range of scientific skills and technological expertise required for a comprehensive view of development and diseases : developmental and stem cell biology, cell and molecular biology, cancer biology, imaging, bioinformatics, human and animal genetics, and drug screening.

In addition to the excellent doctoral training that each beneficiary will follow at his/her University, the network will provide an active training environment, by bringing together selected partners from the academic, industrial and communication sectors, and will stimulate fruitful interactions between the NEUcrest PhD students themselves through regular network-wide events. There will also be a strong emphasis on communication skills and public/patient/clinician outreach. Thus, the NEUcrest ITN will enable the selected PhD students to master scientific and transferable competences indispensable for addressing complex questions in Life Sciences and Human Health, and position them for leading roles in European academia and industry