Name: Partner 5: Universidad Miguel Hernandez de elche, Spain

Address: Avinguda de la Universitat d'Elx, s/n, 03202 Elche, Alicante, Spain

Link: https://www.umh.es/

Summary: The UMH holds the Neurosciences Institute (IN), a joint research Institute (JRI) together with the Spanish National Research Council (CSIC). It is an internationally recognized centre for Neuroscience and Cancer research, holding the “Severo Ochoa Excellence Award”, a very prestigious award only given to 25 Institutions nationwide. M Angela NIETO research group has been studying cell movements and plasticity more than 20 years. In particular, they have studied the epithelial to mesenchymal transition (EMT) during embryonic development since their description of the Snail family of transcription factors and their involvement in the development and migration of the neural crest in 1994. Their main contribution has been the impact that the reactivation of this developmental program has in adult disease, as they made the connection with tumour progression. In the last ten years, they have continued describing new developmental EMTs and extended the concept of its reactivation in pathologies related to bone development and homeostasis and also organ degeneration (fibrosis), opening new avenues for antimetastatic and antifibrotic therapies.

Neural crest, EMT and cancer: Prof. Angela NIETO research group has been studying cell movements and plasticity more than 20 years. In particular, they have studied the epithelial to mesenchymal transition (EMT) during embryonic development since their description of the Snail family of transcription factors and their involvement in the development and migration of the neural crest in 1994. Their main contribution has been the impact that the reactivation of this developmental program has in adult disease, as they made the connection with tumour progression. In the last ten years, they have continued describing new developmental EMTs and extended the concept of its reactivation in pathologies related to bone development and homeostasis and also organ degeneration (fibrosis), opening new avenues for antimetastatic and antifibrotic therapies.

Prof. Nieto’s lab will be hosting the young researchers ESR9 and ESR10.

Click here for research team details